Advertising is not just giving a link to another site - some sites are well known to the extent that nicknames are just as bad. The usual punishments apply here as they do to giving links.
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It actually is a joke! One of my pharmacy professors explained it to us once and it is hilarious.The joke is that the physics professor and the assistant are actually taking aspirin (presumably for a headache). Aspirin is a salicyclic acid that has a hydroxyl ion added to it (which is liberated when you ingest it).Once you've taken aspirin, its breakdown occurs when plasma esterases hydrolyze (giving it an hydroxyl ion) the salicylic acid, thus stopping its effects and giving you your headache back.When the professor says "that's no hydroxyl ion, that's my wife!" He's saying that its not the breakdown of the aspirin that's making his headache return, it's his wife!edit TL;DR: His wife is giving him a headache